|The GENIUS grid portal allows grid users to access the power of Rosetta software at the click of a button.
Courtesy of GILDA and INFN; larger version at SciVee
To allow the wider biological community to run this software using a user friendly interface
, the Rosetta ab initio application has been integrated in to the GENIUS Grid Portal
, developed as a collaboration between the Italian INFN Grid project and based on the NICE EnginFrame Grid Portal, developed by grid technology company
Thanks to this grid portal
, non-expert users using a conventional web browser can access the grid infrastructure to execute and monitor their protein prediction jobs. GENIUS hides all the complexity of the underlying grid infrastructure from the user
, leaving researchers free to concentrate on their results.
In our context
, given the huge number of NBP sequences to be simulated
, we have set up an automatic procedure for generating parametric JDL files on the GENIUS Grid Portal. This procedure exploits the features introduced by the last release of the gLite middleware
, allowing biologists to create and submit parametric jobs to the grid. Each submitted job then independently predicts a protein structure.
- Fabio Polticelli
, Pier Luigi Luisi
and Giovanni Mivervini, Computational Biochemistry Lab, Roma 3, Italy; and Giuseppe la Rocca
, GILDA, Italy